Please use this identifier to cite or link to this item:
|Title:||Cell cycle synchronization of stem cells using inertial microfluidics|
Van Vliet, K.J.
|Source:||Lee, W.C.,Bhagat, A.A.S.,Huang, S.,Van Vliet, K.J.,Han, J.,Lim, C.T. (2010). Cell cycle synchronization of stem cells using inertial microfluidics. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 1 : 208-210. ScholarBank@NUS Repository.|
|Abstract:||Cell cycle synchronization is of paramount importance for studying cellular properties and biological processes involved in various stages of the cell cycle. Here, we present a microfluidics based approach to synchronize the cell cycle of a primary - cells, human bone marrow-derived mesenchymal stem cells (hMSCs), using inertial forces in spiral microchan-nels. The device operating principle exploits the relationship between the volume (and thus diameter) of a cell and its phase in the cell cycle, in order to fractionate hMSCs populations into synchronized subpopulations enriched in cell cycle fractions of G0/G1, S and G2/M phases.|
|Source Title:||14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Dec 9, 2017
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.