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Title: Delivery of drugs and biomolecules using carbon nanotubes
Authors: Vashist, S.K.
Zheng, D.
Pastorin, G. 
Al-Rubeaan, K.
Luong, J.H.T.
Sheu, F.-S. 
Issue Date: Nov-2011
Source: Vashist, S.K., Zheng, D., Pastorin, G., Al-Rubeaan, K., Luong, J.H.T., Sheu, F.-S. (2011-11). Delivery of drugs and biomolecules using carbon nanotubes. Carbon 49 (13) : 4077-4097. ScholarBank@NUS Repository.
Abstract: Carbon nanotubes (CNTs) have emerged as one of the most advanced nanovectors for the highly efficient delivery of drugs and biomolecules. They offer several appealing features such as large surface areas with well defined physico-chemical properties as well as unique optical and electrical properties. They can be conjugated non-covalently or covalently with drugs, biomolecules and nanoparticles. Albeit some pending concerns about their toxicity in vitro and in vivo, functionalized CNTs appear to exhibit very low toxicity and are not immunogenic. Thus, they could be promising carriers with a great potential for the development of a new-generation delivery system for drugs and biomolecules. There have been significant advances in the field of CNT-based drug delivery, especially in the specific targeting of anticancer and anti-inflammatory drugs for tissues and organs in the body, where their therapeutic effect is highly required. Other promising applications are the delivery of DNA, RNA and proteins. © 2011 Published by Elsevier Ltd. All rights reserved.
Source Title: Carbon
ISSN: 00086223
DOI: 10.1016/j.carbon.2011.05.049
Appears in Collections:Staff Publications

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