Please use this identifier to cite or link to this item: https://doi.org/10.1007/s00253-009-2192-4
Title: Biodegradation of aromatic compounds: Current status and opportunities for biomolecular approaches
Authors: Cao, B.
Nagarajan, K.
Loh, K.-C. 
Keywords: Aromatics
Biodegradation
Metabolic engineering
Molecular approaches
Omics technologies
Protein engineering
Issue Date: Nov-2009
Source: Cao, B., Nagarajan, K., Loh, K.-C. (2009-11). Biodegradation of aromatic compounds: Current status and opportunities for biomolecular approaches. Applied Microbiology and Biotechnology 85 (2) : 207-228. ScholarBank@NUS Repository. https://doi.org/10.1007/s00253-009-2192-4
Abstract: Biodegradation can achieve complete and cost-effective elimination of aromatic pollutants through harnessing diverse microbial metabolic processes. Aromatics biodegradation plays an important role in environmental cleanup and has been extensively studied since the inception of biodegradation. These studies, however, are diverse and scattered; there is an imperative need to consolidate, summarize, and review the current status of aromatics biodegradation. The first part of this review briefly discusses the catabolic mechanisms and describes the current status of aromatics biodegradation. Emphasis is placed on monocyclic, polycyclic, and chlorinated aromatic hydrocarbons because they are the most prevalent aromatic contaminants in the environment. Among monocyclic aromatic hydrocarbons, benzene, toluene, ethylbenzene, and xylene; phenylacetic acid; and structurally related aromatic compounds are highlighted. In addition, biofilms and their applications in biodegradation of aromatic compounds are briefly discussed. In recent years, various biomolecular approaches have been applied to design and understand microorganisms for enhanced biodegradation. In the second part of this review, biomolecular approaches, their applications in aromatics biodegradation, and associated biosafety issues are discussed. Particular attention is given to the applications of metabolic engineering, protein engineering, and "omics" technologies in aromatics biodegradation. © 2009 Springer-Verlag.
Source Title: Applied Microbiology and Biotechnology
URI: http://scholarbank.nus.edu.sg/handle/10635/67843
ISSN: 01757598
DOI: 10.1007/s00253-009-2192-4
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