Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/67026
Title: Elliptically polarized coherent anti-Stokes Raman scattering microscopy
Authors: Lu, F. 
Zheng, W. 
Huang, Z. 
Issue Date: 1-Dec-2008
Source: Lu, F.,Zheng, W.,Huang, Z. (2008-12-01). Elliptically polarized coherent anti-Stokes Raman scattering microscopy. Optics Letters 33 (23) : 2842-2844. ScholarBank@NUS Repository.
Abstract: We report an approach to coherent anti-Stokes Raman scattering (CARS) microscopy that significantly suppresses the nonresonant background for high-contrast vibrational imaging. We employ an elliptically polarized pump field with an aspect ratio of 1 : √3 of the ellipse combined with a linearly polarized Stokes field for elliptically polarized CARS (EP-CARS) microscopy. The EP-CARS technique yields a 6-7-fold improvement in signal-to-background ratios compared with normal CARS, while providing an approximately 1.25-fold improvement in resonant CARS signal compared with normal polarization-sensitive CARS microscopy. We demonstrate this technique by imaging 1.5 μm polystyrene beads in water and lipid droplets in unstained fibroblast cells. © 2008 Optical Society of America.
Source Title: Optics Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/67026
ISSN: 01469592
Appears in Collections:Staff Publications

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