Please use this identifier to cite or link to this item: https://doi.org/10.1364/BOE.4.001683
Title: Dark-field circular depolarization optical coherence microscopy
Authors: Mehta, K.
Zhang, P.
Yeo, E.L.L.
Kah, J.C.Y.
Chen, N. 
Issue Date: 2013
Source: Mehta, K., Zhang, P., Yeo, E.L.L., Kah, J.C.Y., Chen, N. (2013). Dark-field circular depolarization optical coherence microscopy. Biomedical Optics Express 4 (9) : 1683-1691. ScholarBank@NUS Repository. https://doi.org/10.1364/BOE.4.001683
Abstract: Optical coherence microscopy (OCM) is a widely used structural imaging modality. To extend its application in molecular imaging, gold nanorods are widely used as contrast agents for OCM. However, they very often offer limited sensitivity as a result of poor signal to background ratio. Here we experimentally demonstrate that a novel OCM implementation based on dark-field circular depolarization detection can efficiently detect circularly depolarized signal from gold nanorods and at the same time efficiently suppress the background signals. This results into a significant improvement in signal to background ratio. © 2013 Optical Society of America.
Source Title: Biomedical Optics Express
URI: http://scholarbank.nus.edu.sg/handle/10635/66989
ISSN: 21567085
DOI: 10.1364/BOE.4.001683
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