Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0142-9612(00)00310-0
Title: Surface modification of stainless steel by grafting of poly(ethylene glycol) for reduction in protein adsorption
Authors: Zhang, F.
Kang, E.T. 
Neoh, K.G. 
Wang, P. 
Tan, K.L. 
Keywords: Adsorption
Grafting
PEG
Plasma
Protein
Silane
Stainless steel
XPS
Issue Date: 15-Jun-2001
Source: Zhang, F., Kang, E.T., Neoh, K.G., Wang, P., Tan, K.L. (2001-06-15). Surface modification of stainless steel by grafting of poly(ethylene glycol) for reduction in protein adsorption. Biomaterials 22 (12) : 1541-1548. ScholarBank@NUS Repository. https://doi.org/10.1016/S0142-9612(00)00310-0
Abstract: The surface of stainless steel was first modified by the silane coupling agent (SCA), (3-mercaptopropyl)trimethoxysilane. The silanized stainless-steel surface (SCA-SS surface) was subsequently activated by argon plasma and then subjected to UV-induced graft polymerization of poly(ethylene glycol)methacrylate (PEGMA). The chemical structures and composition of the pristine, silane-treated, plasma-treated and PEGMA graft-polymerized stainless-steel coupon surfaces were characterized by X-ray photoelectron spectroscopy (XPS) and attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy. The graft polymerization of PEGMA onto the plasma-pretreated SCA-SS surface was studied with different argon plasma pretreatment time, macromonomer concentration, and UV graft polymerization time. In general, a brief plasma pretreatment, high PEGMA concentration, and long UV graft polymerization time readily resulted in a high graft concentration. The PEGMA graft-polymerized stainless-steel coupon (PEGMA-g-SCA-SS) with a high graft concentration, and thus a high PEG content, was found to be very effective in preventing bovine serum albumin and γ-globulin adsorption. Copyright © 2001 Elsevier Science Ltd.
Source Title: Biomaterials
URI: http://scholarbank.nus.edu.sg/handle/10635/66844
ISSN: 01429612
DOI: 10.1016/S0142-9612(00)00310-0
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