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Title: Nanocrystalline nickel ferrite particles synthesized by non-hydrolytic sol-gel method and their composite with biodegradable polymer
Authors: Yin, H.
Casey, P.S.
Chow, G.M. 
Keywords: Composite
Nickel ferrite
Non-hydrolytic sol-gel method
Poly(D L-lactide) PLA
Targeted drug delivery
Issue Date: Nov-2012
Citation: Yin, H., Casey, P.S., Chow, G.M. (2012-11). Nanocrystalline nickel ferrite particles synthesized by non-hydrolytic sol-gel method and their composite with biodegradable polymer. Journal of Nanoscience and Nanotechnology 12 (11) : 8431-8436. ScholarBank@NUS Repository.
Abstract: Targeted drug delivery has been one of the most important biomedical applications for magnetic particles. Such applications require magnetic particles to have functionalized surfaces/surface coatings that facilitate their incorporation into a polymer matrix to produce a polymer composite. In this paper, nanocrystalline nickel ferrite particles with an oleic acid surface coating were synthesized using a non-hydrolytic sol-gel method and incorporated into a biodegradable polymer matrix, poly(D,L-lactide) PLA prepared using a double emulsion method. As-synthesized nickel ferrite particles had a multi-crystalline structure with chemically adsorbed oleic acid on their surface. After forming the PLA composite, nickel ferrite particles were encapsulated in PLA microspheres. At low nickel ferrite concentrations, composites showed very similar surface charges to that of PLA. The composites were magnetically responsive and increasing the nickel ferrite concentration was found to increase magnetization of the composite. Copyright © 2012 American Scientific Publishers.
Source Title: Journal of Nanoscience and Nanotechnology
ISSN: 15334880
DOI: 10.1166/jnn.2012.6682
Appears in Collections:Staff Publications

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