Energy transfer between a cationic-conjugated poly(fluorene-co-phenylene) and thiazole orange for DNA hybridization detection involving G-rich sequences

Please use this identifier to cite or link to this item: https://doi.org/10.1002/marc.200700344

Title:	Energy transfer between a cationic-conjugated poly(fluorene-co-phenylene) and thiazole orange for DNA hybridization detection involving G-rich sequences
Authors:	Liu, B. Bazan, G.C.
Keywords:	Fluorescence resonance energy transfer Self-assembly Sensors Thiazole orange Water-soluble conjugated polymers
Issue Date:	3-Sep-2007
Citation:	Liu, B., Bazan, G.C. (2007-09-03). Energy transfer between a cationic-conjugated poly(fluorene-co-phenylene) and thiazole orange for DNA hybridization detection involving G-rich sequences. Macromolecular Rapid Communications 28 (17) : 1804-1808. ScholarBank@NUS Repository. https://doi.org/10.1002/marc.200700344
Abstract:	Efficient energy transfer between a cationic poly(fluorene-co-phenylene) and thiazole orange mediated by a G-rich oligonucleotide provided sensitized TO emission over 25 000-fold more intense than that from free TO. Higher energy transfer efficiency to ssDNA/TO relative to dsDNA/TO leads to an improved sensitivity and selectivity in G-rich DNA hybridization detection as compared to the direct use of TO as the signal reporter. The signal amplification provided by conjugated polymers is useful to amplify the response from other TO-based detection protocols. © 2007 WILEY-VCH Verlag GmbH & Co. KGaA.
Source Title:	Macromolecular Rapid Communications
URI:	http://scholarbank.nus.edu.sg/handle/10635/63834
ISSN:	10221336
DOI:	10.1002/marc.200700344
Appears in Collections:	Staff Publications

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