Please use this identifier to cite or link to this item: https://doi.org/10.1089/ten.2005.11.101
Title: Potential of nanofiber matrix as tissue-engineering scaffolds
Authors: Ma, Z. 
Kotaki, M. 
Inai, R.
Ramakrishna, S. 
Issue Date: Jan-2005
Citation: Ma, Z., Kotaki, M., Inai, R., Ramakrishna, S. (2005-01). Potential of nanofiber matrix as tissue-engineering scaffolds. Tissue Engineering 11 (1-2) : 101-109. ScholarBank@NUS Repository. https://doi.org/10.1089/ten.2005.11.101
Abstract: Tissue-engineering scaffolds should be analogous to native extracellular matrix (ECM) in terms of both chemical composition and physical structure. Polymeric nanofiber matrix is similar, with its nanoscaled nonwoven fibrous ECM proteins, and thus is a candidate ECM-mimetic material. Techniques such as electrospinning to produce polymeric nanofibers have stimulated researchers to explore the application of nanofiber matrix as a tissue-engineering scaffold. This review covers the preparation and modification of polymeric nanofiber matrix in the development of future tissue-engineering scaffolds. Major emphasis is also given to the development and applications of aligned, core shell-structured, or surface-functionalized polymer nanofibers. The potential application of polymer nanofibers extends far beyond tissue engineering. Owing to their high surface area, functionalized polymer nanofibers will find broad applications as drug delivery carriers, biosensors, and molecular filtration membranes in future.
Source Title: Tissue Engineering
URI: http://scholarbank.nus.edu.sg/handle/10635/61131
ISSN: 10763279
DOI: 10.1089/ten.2005.11.101
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