Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.jmbbm.2013.01.008
Title: Liver tissue characterization from uniaxial stress-strain data using probabilistic and inverse finite element methods
Authors: Fu, Y.B.
Chui, C.K. 
Teo, C.L. 
Keywords: Finite element analysis
Liver
Nondeterministic approach
Tissue modeling
Uncertainty analysis
Issue Date: Apr-2013
Source: Fu, Y.B., Chui, C.K., Teo, C.L. (2013-04). Liver tissue characterization from uniaxial stress-strain data using probabilistic and inverse finite element methods. Journal of the Mechanical Behavior of Biomedical Materials 20 : 105-112. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jmbbm.2013.01.008
Abstract: Biological soft tissue is highly inhomogeneous with scattered stress-strain curves. Assuming that the instantaneous strain at a specific stress varies according to a normal distribution, a nondeterministic approach is proposed to model the scattered stress-strain relationship of the tissue samples under compression. Material parameters of the liver tissue modeled using Mooney-Rivlin hyperelastic constitutive equation were represented by a statistical function with normal distribution. Mean and standard deviation of the material parameters were determined using inverse finite element method and inverse mean-value first-order second-moment (IMVFOSM) method respectively. This method was verified using computer simulation based on direct Monte-Carlo (MC) method. The simulated cumulative distribution function (CDF) corresponded well with that of the experimental stress-strain data. The resultant nondeterministic material parameters were able to model the stress-strain curves from other separately conducted liver tissue compression tests. Stress-strain data from these new tests could be predicted using the nondeterministic material parameters. © 2013 Elsevier Ltd.
Source Title: Journal of the Mechanical Behavior of Biomedical Materials
URI: http://scholarbank.nus.edu.sg/handle/10635/60653
ISSN: 17516161
DOI: 10.1016/j.jmbbm.2013.01.008
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