Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.tsf.2010.11.035
Title: Electrospray deposition of nanohydroxyapatite coatings: A strategy to mimic bone apatite mineral
Authors: Thian, E.S. 
Li, X.
Huang, J.
Edirisinghe, M.J.
Bonfield, W.
Best, S.M.
Keywords: Bioactivity
Coatings
Electrospray deposition
Hydroxyapatite
Simulated body fluid
Issue Date: 31-Jan-2011
Source: Thian, E.S., Li, X., Huang, J., Edirisinghe, M.J., Bonfield, W., Best, S.M. (2011-01-31). Electrospray deposition of nanohydroxyapatite coatings: A strategy to mimic bone apatite mineral. Thin Solid Films 519 (7) : 2328-2331. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tsf.2010.11.035
Abstract: The biological performance of orthopaedic and oral metallic implants can be enhanced significantly by the application of bioactive coatings. In this work, a cost-efficient alternative to the traditional technique to produce a hydroxyapatite (HA) coating with a nanostructured feature onto a metallic implant surface at room temperature via electrospray deposition, is presented. To evaluate the bioactive capacity of these nanoHA (nHA) coatings in vitro, an acellular simulated body fluid soaking experiment and a human osteoblast (HOB) cell culture work were conducted. Under these physiological conditions, the accelerated apatite precipitation process occurred on the nHA-coated titanium surfaces as compared to the uncoated titanium surfaces. HOB cells developed mature cytoskeletons with distinct evidence of actin stress fibres and vinculin adhesion plaques, on these nHA coatings. Hence, this deposition technique holds great potential in producing high quality nHA coatings for biomedical applications. © 2010 Elsevier B.V. All rights reserved.
Source Title: Thin Solid Films
URI: http://scholarbank.nus.edu.sg/handle/10635/60145
ISSN: 00406090
DOI: 10.1016/j.tsf.2010.11.035
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

14
checked on Dec 6, 2017

WEB OF SCIENCETM
Citations

14
checked on Nov 22, 2017

Page view(s)

37
checked on Dec 10, 2017

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.