Please use this identifier to cite or link to this item:
|Title:||A systematic review and meta-analysis comparing laparoscopic versus open gastric resections for gastrointestinal stromal tumors of the stomach|
|Citation:||Koh, Y.-X., Chok, A.-Y., Zheng, H.-L., Tan, C.-S., Chow, P.K.H., Wong, W.-K., Goh, B.K.P. (2013-10). A systematic review and meta-analysis comparing laparoscopic versus open gastric resections for gastrointestinal stromal tumors of the stomach. Annals of Surgical Oncology 20 (11) : 3549-3560. ScholarBank@NUS Repository. https://doi.org/10.1245/s10434-013-3051-1|
|Abstract:||Background: This study is a systematic review and meta-analysis that compares the short- and long-term outcomes of laparoscopic gastric resection (LR) versus open gastric resection (OR) for gastric gastrointestinal stromal tumors (GISTs). Methods: Comparative studies reporting the outcomes of LR and OR for GIST were reviewed. Results: A total of 11 nonrandomized studies reviewed 765 patients: 381 LR and 384 OR. A higher proportion of high-risk tumors and gastrectomies were in the OR compared with LR (odds ratio, 3.348; 95 % CI, 1.248-8.983; p =.016) and (odds ratio,.169; 95 % CI,.090-.315; p <.001), respectively. Intraoperative blood loss was significantly lower in the LR group [weighted mean difference (WMD), -86.508 ml; 95 % CI, -141.184 to -31.831 ml; p <.002]. The LR group was associated with a significantly lower risk of minor complications (odds ratio,.517; 95 % CI,.277-.965; p =.038), a decreased postoperative hospital stay (WMD, -3.421 days; 95 % CI, -4.737 to -2.104 days; p <.001), a shorter time to first flatus (WMD, -1.395 days; 95 % CI, -1.655 to -1.135 days; p <.001), and shorter time for resumption of oral intake (WMD, -1.887 days; 95 % CI, -2.785 to -.989 days; p <.001). There was no statistically significant difference between the two groups with regard to operation time (WMD, 5.731 min; 95 % CI, -15.354-26.815 min; p =.594), rate of major complications (odds ratio,.631; 95 % CI,.202-1.969; p =.428), margin positivity (odds ratio,.501; 95 % CI,.157-1.603; p =.244), local recurrence rate (odds ratio,.629; 95 % CI,.208-1.903; p =.412), recurrence-free survival (RFS) (odds ratio, 1.28; 95 % CI,.705-2.325; p =.417), and overall survival (OS) (odds ratio, 1.879; 95 % CI,.591-5.979; p =.285). Conclusions: LR results in superior short-term postoperative outcomes without compromising oncological safety and long-term oncological outcomes compared with OR. © 2013 Society of Surgical Oncology.|
|Source Title:||Annals of Surgical Oncology|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jul 17, 2018
WEB OF SCIENCETM
checked on Jun 27, 2018
checked on Jun 8, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.