Please use this identifier to cite or link to this item:
|Title:||Myopia and cognitive dysfunction: The Singapore Malay eye study|
|Citation:||Ong, S.-Y., Ikram, M.K., Haaland, B.A., Cheng, C.-Y., Saw, S.-M., Wong, T.Y., Cheung, C.Y. (2013-01). Myopia and cognitive dysfunction: The Singapore Malay eye study. Investigative Ophthalmology and Visual Science 54 (1) : 799-803. ScholarBank@NUS Repository. https://doi.org/10.1167/iovs.12-10460|
|Abstract:||PURPOSE. To investigate a possible relationship between refractive error and cognitive function. METHODS. This population-based, cross-sectional study included 1032 persons aged 60 to 79 who participated in the Singapore Malay Eye Study. Refraction (sphere, cylinder, and axis) was measured using an autorefractor, and spherical equivalent was defined as sphere plus half negative cylinder. Refractive errors were defined as myopia (spherical equivalent < -0.5), emmetropia (-0.5 diopter [D] ≤ spherical equivalent ≤ 0.5 D), and hyperopia (spherical equivalent > 0.5 D). Visual acuity was measured with a logMAR chart. Cognitive dysfunction, assessed using the Abbreviated Mental Test, was defined based on education-specific cutoff values. RESULTS. Compared with individuals with emmetropia, persons with myopia were almost twice as likely to have cognitive dysfunction (odds ratio 1.82; 95% confidence interval 1.05- 3.15), after adjusting for age, sex, body mass index, income, education, and hours of reading and writing per day. Hyperopia was not associated with cognitive dysfunction. The association remained significant after further adjustment for uncorrected refractive errors or best-corrected visual acuity. CONCLUSIONS. Our results provide evidence on a novel association between myopia and cognitive dysfunction. Copyright 2013 The Association for Research in Vision and Ophthalmology, Inc.|
|Source Title:||Investigative Ophthalmology and Visual Science|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Dec 10, 2018
WEB OF SCIENCETM
checked on Nov 26, 2018
checked on Nov 17, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.