Please use this identifier to cite or link to this item: https://doi.org/10.3201/eid1708.101270
Title: Risk factors for pandemic (H1N1) 2009 seroconversion among adults, Singapore, 2009
Authors: Lim, W.-Y. 
Chen, C.H.J.
Ma, Y.
Chen, M.I.C. 
Lee, V.J.M. 
Cook, A.R. 
Tan, L.W.L.
Tabo, N.F.
Barr, I.
Cui, L.
Lin, R.T.P.
Leo, Y.S.
Chia Jr., K.S. 
Issue Date: Aug-2011
Source: Lim, W.-Y., Chen, C.H.J., Ma, Y., Chen, M.I.C., Lee, V.J.M., Cook, A.R., Tan, L.W.L., Tabo, N.F., Barr, I., Cui, L., Lin, R.T.P., Leo, Y.S., Chia Jr., K.S. (2011-08). Risk factors for pandemic (H1N1) 2009 seroconversion among adults, Singapore, 2009. Emerging Infectious Diseases 17 (8) : 1455-1462. ScholarBank@NUS Repository. https://doi.org/10.3201/eid1708.101270
Abstract: A total of 828 community-dwelling adults were studied during the course of the pandemic (H1N1) 2009 outbreak in Singapore during June-September 2009. Baseline blood samples were obtained before the outbreak, and 2 additional samples were obtained during follow-up. Seroconversion was defined as a ≥4-fold increase in antibody titers to pandemic (H1N1) 2009, determined by using hemagglutination inhibition. Men were more likely than women to seroconvert (mean adjusted hazards ratio [HR] 2.23, mean 95% confidence interval [CI] 1.26-3.93); Malays were more likely than Chinese to seroconvert (HR 2.67, 95% CI 1.04-6.91). Travel outside Singapore during the study period was associated with seroconversion (HR 1.76, 95% CI 1.11-2.78) as was use of public transport (HR 1.81, 95% CI 1.05-3.09). High baseline antibody titers were associated with reduced seroconversion. This study suggests possible areas for intervention to reduce transmission during future influenza outbreaks.
Source Title: Emerging Infectious Diseases
URI: http://scholarbank.nus.edu.sg/handle/10635/53137
ISSN: 10806040
DOI: 10.3201/eid1708.101270
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

13
checked on Dec 13, 2017

WEB OF SCIENCETM
Citations

11
checked on Nov 15, 2017

Page view(s)

35
checked on Dec 16, 2017

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.