Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/52599
Title: Modeling of environmentally sensitive hydrogels for drug delivery: An overview and recent developments
Authors: Li, H. 
Luo, R.
Lam, K.Y. 
Keywords: Bioseparation
Drug delivery system
Fick's Law
Flory-Huggins interaction
Langmuir Theory
Peppas Model
Power Law
Issue Date: Mar-2006
Source: Li, H.,Luo, R.,Lam, K.Y. (2006-03). Modeling of environmentally sensitive hydrogels for drug delivery: An overview and recent developments. Frontiers in Drug Design and Discovery 2 (1) : 295-331. ScholarBank@NUS Repository.
Abstract: A critical review of mathematical modeling for simulation of environmentally sensitive hydrogels is presented for application of drug delivery. The review demonstrates that there have been large numbers of published studies on the model development, although the majority of investigations in the research area of the drug delivery are experimental-based. Therefore, a systematical review of mathematical modeling of environmentally sensitive hydrogels is necessarily provided through comprehensive assessment on several critical developments of mathematical models to simulate the hydrogels for mechanisms of drug release. The present review classifies the developed models into the fundamental and empirical/semi-empirical groups and also discusses the properties and performance of the hydrogels as drug delivery system in kinetics and equilibrium. All rights reserved - © 2006 Bentham Science Publishers.
Source Title: Frontiers in Drug Design and Discovery
URI: http://scholarbank.nus.edu.sg/handle/10635/52599
ISSN: 15672042
Appears in Collections:Staff Publications

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