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https://doi.org/10.1002/smll.201002298
| Title: | Bio-inspired micropatterned platform to steer stem cell differentiation | Authors: | Tay, C.Y. Pal, M. Yu, H. Leong, W.S. Tan, N.S. Ng, K.W. Venkatraman, S. Boey, F. Leong, D.T. Tan, L.P. |
Keywords: | biomaterials biomimetics microcontact printing micropatterning stem cells |
Issue Date: | 23-May-2011 | Citation: | Tay, C.Y., Pal, M., Yu, H., Leong, W.S., Tan, N.S., Ng, K.W., Venkatraman, S., Boey, F., Leong, D.T., Tan, L.P. (2011-05-23). Bio-inspired micropatterned platform to steer stem cell differentiation. Small 7 (10) : 1416-1421. ScholarBank@NUS Repository. https://doi.org/10.1002/smll.201002298 | Abstract: | Controlled stem cell differentiation on micropatterned biodegradable substrates involves modulation of the canonical FAK-ERK (focal adhesion kinase-extracellular-signal regulated kinase) signaling pathway in the absence of exogenous soluble factors. The use of a micropatterned platform to coerce human mesenchymal stem cells to adopt an elongated morphology bypasses the need to use pharmacological factors to repress FAK-ERK signaling activity to bring about substantial myogenesis. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. | Source Title: | Small | URI: | http://scholarbank.nus.edu.sg/handle/10635/51760 | ISSN: | 16136810 | DOI: | 10.1002/smll.201002298 |
| Appears in Collections: | Staff Publications |
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