Please use this identifier to cite or link to this item: https://doi.org/10.1002/smll.201002298
Title: Bio-inspired micropatterned platform to steer stem cell differentiation
Authors: Tay, C.Y.
Pal, M.
Yu, H.
Leong, W.S.
Tan, N.S.
Ng, K.W.
Venkatraman, S.
Boey, F.
Leong, D.T. 
Tan, L.P.
Keywords: biomaterials
biomimetics
microcontact printing
micropatterning
stem cells
Issue Date: 23-May-2011
Citation: Tay, C.Y., Pal, M., Yu, H., Leong, W.S., Tan, N.S., Ng, K.W., Venkatraman, S., Boey, F., Leong, D.T., Tan, L.P. (2011-05-23). Bio-inspired micropatterned platform to steer stem cell differentiation. Small 7 (10) : 1416-1421. ScholarBank@NUS Repository. https://doi.org/10.1002/smll.201002298
Abstract: Controlled stem cell differentiation on micropatterned biodegradable substrates involves modulation of the canonical FAK-ERK (focal adhesion kinase-extracellular-signal regulated kinase) signaling pathway in the absence of exogenous soluble factors. The use of a micropatterned platform to coerce human mesenchymal stem cells to adopt an elongated morphology bypasses the need to use pharmacological factors to repress FAK-ERK signaling activity to bring about substantial myogenesis. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title: Small
URI: http://scholarbank.nus.edu.sg/handle/10635/51760
ISSN: 16136810
DOI: 10.1002/smll.201002298
Appears in Collections:Staff Publications

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