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|Title:||Bio-inspired micropatterned platform to steer stem cell differentiation|
|Source:||Tay, C.Y., Pal, M., Yu, H., Leong, W.S., Tan, N.S., Ng, K.W., Venkatraman, S., Boey, F., Leong, D.T., Tan, L.P. (2011-05-23). Bio-inspired micropatterned platform to steer stem cell differentiation. Small 7 (10) : 1416-1421. ScholarBank@NUS Repository. https://doi.org/10.1002/smll.201002298|
|Abstract:||Controlled stem cell differentiation on micropatterned biodegradable substrates involves modulation of the canonical FAK-ERK (focal adhesion kinase-extracellular-signal regulated kinase) signaling pathway in the absence of exogenous soluble factors. The use of a micropatterned platform to coerce human mesenchymal stem cells to adopt an elongated morphology bypasses the need to use pharmacological factors to repress FAK-ERK signaling activity to bring about substantial myogenesis. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.|
|Appears in Collections:||Staff Publications|
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