Please use this identifier to cite or link to this item: https://doi.org/10.1109/ICARCV.2010.5707891
Title: Speed optimization for micropipette motion during zebrafish embryo microinjection
Authors: Zhou, S.
Chen, P. 
Lu, Z.
Hoo, N.J.
Luo, H.
Ge, R. 
Ong, C.J. 
Lin, W.
Keywords: Microinjection
Speed optimization
Viscoelastic model
Issue Date: 2010
Citation: Zhou, S.,Chen, P.,Lu, Z.,Hoo, N.J.,Luo, H.,Ge, R.,Ong, C.J.,Lin, W. (2010). Speed optimization for micropipette motion during zebrafish embryo microinjection. 11th International Conference on Control, Automation, Robotics and Vision, ICARCV 2010 : 364-369. ScholarBank@NUS Repository. https://doi.org/10.1109/ICARCV.2010.5707891
Abstract: This paper presents an approach to optimize the zebrafish-embryo microinjection process by selecting suitable speed trajectories for the motion of the micropipette, with the objective of minimizing the risk of damaging the embryo during the microinjection process. A viscoelastic model of a zebrafish embryo is developed based on experimental data. The speed optimization problem is formulated based on this viscoelastic model. Simulation results indicate that there exists an optimal speed trajectory for the micropipette under certain conditions. The key benefit of this speed optimization approach is that the turgor pressure inside the membrane is prevented from increasing significantly during the microinjection process, thus avoiding damaging the biological components in the embryo. ©2010 IEEE.
Source Title: 11th International Conference on Control, Automation, Robotics and Vision, ICARCV 2010
URI: http://scholarbank.nus.edu.sg/handle/10635/51650
ISBN: 9781424478132
DOI: 10.1109/ICARCV.2010.5707891
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