Please use this identifier to cite or link to this item: https://doi.org/10.1080/15376490500259335
Title: Finite element simulation of the micropipette aspiration of a living cell undergoing large viscoelastic deformation
Authors: Zhou, E.H.
Lim, C.T. 
Quek, S.T. 
Issue Date: Nov-2005
Citation: Zhou, E.H., Lim, C.T., Quek, S.T. (2005-11). Finite element simulation of the micropipette aspiration of a living cell undergoing large viscoelastic deformation. Mechanics of Advanced Materials and Structures 12 (6) : 501-512. ScholarBank@NUS Repository. https://doi.org/10.1080/15376490500259335
Abstract: Experiments and computational modeling in single cell mechanics are increasingly being used to evaluate the mechanical properties of living cells such as neutrophils, erythrocytes and fibroblasts. Here, we perform modeling of the micropipette aspiration experiment which has been widely used for measuring the viscoelastic properties of single cells. The commonly used standard linear solid model is extended into the standard neo-Hookean solid model and the large deformation of anchorage-dependent cells in response to micropipette aspiration is simulated. The effects of pipette radius and fillet radius on the rheological behaviour of the cell are also systematically studied. Based on the finite element results, three relationships are derived for the interpretation of the mechanical parameters from the micropipette aspiration of cytoskeleton-rich eukaryotic cells.
Source Title: Mechanics of Advanced Materials and Structures
URI: http://scholarbank.nus.edu.sg/handle/10635/50700
ISSN: 15376494
DOI: 10.1080/15376490500259335
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

42
checked on Oct 23, 2018

WEB OF SCIENCETM
Citations

36
checked on Oct 23, 2018

Page view(s)

79
checked on Oct 20, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.