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Title: Efficacy of silver diamine fluoride for arresting caries treatment
Authors: Yee, R. 
Holmgren, C.
Mulder, J.
Lama, D.
Walker, D.
Helderman, W.V.P.
Keywords: Arresting caries treatment
Clinical trial
Silver diamine fluoride
Issue Date: 2009
Source: Yee, R., Holmgren, C., Mulder, J., Lama, D., Walker, D., Helderman, W.V.P. (2009). Efficacy of silver diamine fluoride for arresting caries treatment. Journal of Dental Research 88 (7) : 644-647. ScholarBank@NUS Repository.
Abstract: Arresting Caries Treatment (ACT) has been proposed to manage untreated dental caries in children. This prospective randomized clinical trial investigated the caries-arresting effectiveness of a single spot application of: (1) 38% silver diamine fluoride (SDF) with tannic acid as a reducing agent; (2) 38% SDF alone; (3) 12% SDF alone; and (4) no SDF application in primary teeth of 976 Nepalese schoolchildren. The a priori null hypothesis was that the different treatments have no effect in arresting active cavitated caries. Only the single application of 38% > SDF with or without tannic acid was effective in arresting caries after 6 months (4.5 and 4.2 mean number of arrested surfaces; p < 0.001), after 1 year (4.1 and 3.4; p < 0.001), and after 2 years (2.2 and 2.1; p < 0.01). Tannic acid conferred no additional benefit. ACT with 38%o SDF provides an alternative when restorative treatment for primary teeth is not an option.
Source Title: Journal of Dental Research
ISSN: 00220345
DOI: 10.1177/0022034509338671
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