Please use this identifier to cite or link to this item: https://doi.org/10.1016/0304-3940(94)90793-5
Title: Preprotachykinin-A and substance P receptor (NK1) gene expression in rat astrocytes in vitro
Authors: Too, H.-P. 
Marriott, D.R.
Wilkin, G.P.
Keywords: Astrocyte
Polymerase chain reaction
Preprotachykinin-A
Substance P
Substance P receptor
Issue Date: 1994
Source: Too, H.-P., Marriott, D.R., Wilkin, G.P. (1994). Preprotachykinin-A and substance P receptor (NK1) gene expression in rat astrocytes in vitro. Neuroscience Letters 182 (2) : 185-187. ScholarBank@NUS Repository. https://doi.org/10.1016/0304-3940(94)90793-5
Abstract: The presence of mRNA transcripts coding for preprotachykinin-A and the substance P receptor in cultured astrocytes is demonstrated by a combination of reverse transcription/polymerase chain reaction (PCR) and Southern blotting. These findings showed that astroyctes in culture are capable of synthesing both the precursor of substance P (preprotachykinin-A) and the cognate receptor, substance P receptor (NK1). The simultaneous presence of both the ligand (substance P) and the receptor (NK1)) may indicate an autocrine nature of astrocyte communication.
Source Title: Neuroscience Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/38252
ISSN: 03043940
DOI: 10.1016/0304-3940(94)90793-5
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