Preprotachykinin-A and substance P receptor (NK1) gene expression in rat astrocytes in vitro

Please use this identifier to cite or link to this item: https://doi.org/10.1016/0304-3940(94)90793-5

Title:	Preprotachykinin-A and substance P receptor (NK1) gene expression in rat astrocytes in vitro
Authors:	Too, H.-P. Marriott, D.R. Wilkin, G.P.
Keywords:	Astrocyte Polymerase chain reaction Preprotachykinin-A Substance P Substance P receptor
Issue Date:	1994
Citation:	Too, H.-P., Marriott, D.R., Wilkin, G.P. (1994). Preprotachykinin-A and substance P receptor (NK1) gene expression in rat astrocytes in vitro. Neuroscience Letters 182 (2) : 185-187. ScholarBank@NUS Repository. https://doi.org/10.1016/0304-3940(94)90793-5
Abstract:	The presence of mRNA transcripts coding for preprotachykinin-A and the substance P receptor in cultured astrocytes is demonstrated by a combination of reverse transcription/polymerase chain reaction (PCR) and Southern blotting. These findings showed that astroyctes in culture are capable of synthesing both the precursor of substance P (preprotachykinin-A) and the cognate receptor, substance P receptor (NK1). The simultaneous presence of both the ligand (substance P) and the receptor (NK1)) may indicate an autocrine nature of astrocyte communication.
Source Title:	Neuroscience Letters
URI:	http://scholarbank.nus.edu.sg/handle/10635/38252
ISSN:	03043940
DOI:	10.1016/0304-3940(94)90793-5
Appears in Collections:	Staff Publications

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