Please use this identifier to cite or link to this item:
|Title:||Plasma levels of 13,14-dihydro-15-keto PGE2after vaginal application of a new PGE2film|
|Source:||Prasad, R.N.V., Roy, A.C., Kottegoda, S.R. (1985). Plasma levels of 13,14-dihydro-15-keto PGE2after vaginal application of a new PGE2film. Prostaglandins 29 (2) : 269-272. ScholarBank@NUS Repository. https://doi.org/10.1016/0090-6980(85)90207-2|
|Abstract:||To determine the release and absorption profile of prostaglandin E2 from a new vaginal film formulation containing 850 μg PGE2, serial plasma levels of 13,14-dihydro-15-keto PGE2 were measured by radioimmunoassay in pregnant women between 16 and 18 weeks gestation. A control group, using placebo vaginal film was included in the study. There was a somewhat uniform increase in the plasma levels of the PGE2 metabolite, reaching peak levels between 4 and 6 hours after application of the film. The findings suggest that this drug formulation could be used clinically when slow constant release of the prostaglandin is required over a period of hours such as in pre-induction cervical ripening of term pregnancy.|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Dec 14, 2017
WEB OF SCIENCETM
checked on Nov 17, 2017
checked on Dec 10, 2017
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.