Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0006-8993(00)02001-1
Title: Expression of immunoregulatory cytokines in neurons of the lateral hypothalamic area and amygdaloid nuclear complex of rats immunized against human IgG
Authors: Gao, Y.
Lin, J.-Y.
Ng, Y.-K. 
Ling, E.-A. 
Keywords: Amygdaloid nuclear complex
Cytokine
Lateral hypothalamic area
Neuroimmunoregulation
Issue Date: 2000
Source: Gao, Y.,Lin, J.-Y.,Ng, Y.-K.,Ling, E.-A. (2000). Expression of immunoregulatory cytokines in neurons of the lateral hypothalamic area and amygdaloid nuclear complex of rats immunized against human IgG. Brain Research 859 (2) : 364-368. ScholarBank@NUS Repository. https://doi.org/10.1016/S0006-8993(00)02001-1
Abstract: Present results showed that interleukin-1 (IL-1), IL-6 and transforming growth factor-β (TGF-β) were constitutively expressed in the supraoptic and paraventricular nuclei of the rat hypothalamus. Immunoreactive cells were also detected, but to a lesser extent, in other parts of hypothalamus as well as in the cerebral cortex. In rats immunized with IgG, there was moderate increase in immunoreactivities of the cytokines. A notable feature, however, was the induction of the cytokine expression in the lateral hypothalamic area and the amygdaloid nuclear complex, suggesting that the neurons in these two areas are involved in possible immune regulation. Copyright (C) 2000 Elsevier Science B.V.
Source Title: Brain Research
URI: http://scholarbank.nus.edu.sg/handle/10635/33519
ISSN: 00068993
DOI: 10.1016/S0006-8993(00)02001-1
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