Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/32537
Title: 2-(benzyl)-3-arylbenzofurans as antitumour and hypocholesterolemic agents
Authors: SIM, KENG-YEOW 
KON, OI-LIAN 
TEO, CHIN-CHIN 
NG, SIU-CHOON 
NATARAJAN, SRIKANTH 
Issue Date: 17-Oct-1995
Source: SIM, KENG-YEOW,KON, OI-LIAN,TEO, CHIN-CHIN,NG, SIU-CHOON,NATARAJAN, SRIKANTH (1995-10-17). 2-(benzyl)-3-arylbenzofurans as antitumour and hypocholesterolemic agents. ScholarBank@NUS Repository.
Abstract: The synthesis and the biological evaluation of a series of basic ethers of 2-benzyl-3-arylbenzofurans as antitumor agents is described. These compounds bind significantly to the antiestrogen-binding sites but only poorly to the estrogen receptor sites and are cytotoxic to tumor cells. Some of these compounds also significantly inhibited de novo cholesterol biosynthesis in an estrogen receptor negative lymphoma cell line rich in antiestrogen-binding sites.
URI: http://scholarbank.nus.edu.sg/handle/10635/32537
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
US5459139.PDF356.5 kBAdobe PDF

OPEN

PublishedView/Download

Page view(s)

229
checked on Dec 15, 2017

Download(s)

121
checked on Dec 15, 2017

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.