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|Title:||Effects of kainate on glucose metabolising enzymes in the brain|
|Citation:||Leong, S.F. (1991). Effects of kainate on glucose metabolising enzymes in the brain. Life Sciences 48 (6) : 561-567. ScholarBank@NUS Repository. https://doi.org/10.1016/0024-3205(91)90471-M|
|Abstract:||Hexokinase and glucose-6-phosphate dehydrogenase activities were studied in brain regions after intraventricular injection of kainic acid. Hexokinase activity was decreased by 10-15% in various regions while glucose-6-phosphate dehydrogenase activity remained unaltered. Soluble hexokinase activity, which remained the smaller fraction of total hexokinase activity, showed slightly more dramatic decreases of 15-35% compared to normal activities in brain regions. This decrease of hexokinase activity in the cytosolic compartment could partly account for the kainate-induced decreases seen in glucose metabolism.|
|Source Title:||Life Sciences|
|Appears in Collections:||Staff Publications|
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