Angiopoietin-1 promotes functional neovascularization that relieves ischemia by improving regional reperfusion in a swine chronic myocardial ischemia model

Please use this identifier to cite or link to this item: https://doi.org/10.1007/s11373-006-9082-x

Title:	Angiopoietin-1 promotes functional neovascularization that relieves ischemia by improving regional reperfusion in a swine chronic myocardial ischemia model
Authors:	Shim, W.S.N. Li, W. Zhang, L. Li, S. Ong, H.C. Song, I.-C. Bapna, A. Ge, R. Lim, Y.T. Chuah, S.C. Sim, E.K.W. Wong, P.
Keywords:	Angiogenesis Angiopoietin Ischemia Regional perfuison
Issue Date:	Jul-2006
Citation:	Shim, W.S.N., Li, W., Zhang, L., Li, S., Ong, H.C., Song, I.-C., Bapna, A., Ge, R., Lim, Y.T., Chuah, S.C., Sim, E.K.W., Wong, P. (2006-07). Angiopoietin-1 promotes functional neovascularization that relieves ischemia by improving regional reperfusion in a swine chronic myocardial ischemia model. Journal of Biomedical Science 13 (4) : 579-591. ScholarBank@NUS Repository. https://doi.org/10.1007/s11373-006-9082-x
Abstract:	This study investigates the long-term angiogenic effects of ANG-1 and VEGF in a swine chronic myocardial ischemia model. Four-weeks after gradual occlusion of the left circumflex coronary artery by ameroid constrictor, animals were injected with recombinant adenoviral vectors carrying either human ANG-1 (n=9), human VEGF165 (n=10) or empty vector (n=7) into the left ventricle free wall supplied by the constricted artery. Left ventricular perfusion in animals that received AdANG-1 (3.25±0.16 ml/min/g, p
Source Title:	Journal of Biomedical Science
URI:	http://scholarbank.nus.edu.sg/handle/10635/27021
ISSN:	10217770
DOI:	10.1007/s11373-006-9082-x
Appears in Collections:	Staff Publications Elements

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