Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ajo.2007.07.023
Title: Relationship of Axial Length and Retinal Vascular Caliber in Children
Authors: Cheung, N.
Tikellis, G.
Amirul, Islam F.M.
Wong, T.Y. 
Saw, S.M. 
Wang, J.J.
Mitchell, P.
Issue Date: 2007
Source: Cheung, N., Tikellis, G., Amirul, Islam F.M., Wong, T.Y., Saw, S.M., Wang, J.J., Mitchell, P. (2007). Relationship of Axial Length and Retinal Vascular Caliber in Children. American Journal of Ophthalmology 144 (5). ScholarBank@NUS Repository. https://doi.org/10.1016/j.ajo.2007.07.023
Abstract: Purpose: Previous studies in older adults suggest that longer axial length is associated with narrower arteriolar caliber. In this study, we re-examined this relationship in a cohort of children, while controlling for the effects of ocular magnification. Design: Cross-sectional study of 767 children aged 7 to 9 years. Methods: Retinal vascular calibers were measured from retinal photographs using a computer-based program. Ocular magnification was corrected using the Bengtsson formula. Standardized examination of refraction and ultrasound ocular biometry was performed for all children. Results: In models that adjusted for age, gender, ethnicity, body mass index, blood pressure, and birth weight, longer axial length was associated strongly with narrower retinal arteriolar caliber (3.18-μm decrease per standard deviation increase in axial length; P < .001) and venular caliber (4.62-μm decrease standard deviation increase in axial length; P < .001) before correction for ocular magnification. However, after correction, these associations no longer were significant (0.44 μm; P = .31, change for arteriolar caliber; and 0.70 μm; P = .25, for venular caliber). Conclusions: Our study in children found no association between axial length and retinal vascular caliber after correcting for ocular magnification, suggesting that the previously reported association was likely related to differences in ocular magnification. © 2007 Elsevier Inc. All rights reserved.
Source Title: American Journal of Ophthalmology
URI: http://scholarbank.nus.edu.sg/handle/10635/26634
ISSN: 00029394
DOI: 10.1016/j.ajo.2007.07.023
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

21
checked on Dec 5, 2017

WEB OF SCIENCETM
Citations

22
checked on Nov 14, 2017

Page view(s)

149
checked on Dec 9, 2017

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.