Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ophtha.2007.11.015
Title: Prevalence and Risk Factors for Age-Related Macular Degeneration in an Adult Japanese Population. The Funagata Study
Authors: Kawasaki, R.
Oizumi, T.
Daimon, M.
Kato, T.
Kawata, S.
Kayama, T.
Yamashita, H.
Wang, J.J.
Wong, T.Y. 
Taylor, B.
Mitchell, P.
Ji, G.-j.
Tano, Y.
Issue Date: 2008
Source: Kawasaki, R.,Oizumi, T.,Daimon, M.,Kato, T.,Kawata, S.,Kayama, T.,Yamashita, H.,Wang, J.J.,Wong, T.Y.,Taylor, B.,Mitchell, P.,Ji, G.-j.,Tano, Y. (2008). Prevalence and Risk Factors for Age-Related Macular Degeneration in an Adult Japanese Population. The Funagata Study. Ophthalmology 115 (8). ScholarBank@NUS Repository. https://doi.org/10.1016/j.ophtha.2007.11.015
Abstract: Objective: To describe the prevalence and risk factors for age-related macular degeneration (AMD) in a Japanese population and to compare these with data from a white population. Design: Population-based cross-sectional epidemiologic study. Participants: A population-based sample of Japanese persons 35 years or older from Funagata, Japan. Methods: The Funagata study is a population-based study of 1758 (43% of eligible) Japanese persons 35 years or older from Funagata, Japan. In 2000 to 2002, 1625 (92.4%) participants had a nonmydriatic fundus photograph of one eye with sufficient quality for grading of AMD lesions, using the Wisconsin protocol. Age-standardized prevalence rates compared with the Blue Mountains Eye Study (BMES) population, odds ratios (ORs), and 95% confidence intervals (CIs) were calculated. Risk factors were assessed by logistic regression. Main Outcome Measures: Early and late AMD. Results: Of 1625 participants, early AMD and late AMD were present in 3.5% and 0.5%, respectively. Age-standardized early AMD prevalence in right eyes was 4.1%, similar to the corresponding prevalence of 4.4% in the BMES. For men, age-standardized prevalences of late AMD in right eyes were 1.1% and 1.2% in the BMES; for women, the corresponding prevalences were 0.3% and 2.1%, respectively. Increasing age (per 10 years; gender-adjusted OR, 2.27; 95% CI, 1.10-4.67) and current cigarette smoking (age- and gender-adjusted OR, 5.03; 95% CI, 1.00-25.47) were associated with late AMD. Conclusions: In this Japanese population, prevalence of early AMD was similar to that for whites in the BMES. Although the late AMD prevalence was lower in Japanese women, in Japanese men it was similar to that in whites. This could have resulted from the substantially high proportion of Japanese men who are smokers. Cigarette smoking and increasing age were the 2 principal factors found associated with late AMD. © 2008 American Academy of Ophthalmology.
Source Title: Ophthalmology
URI: http://scholarbank.nus.edu.sg/handle/10635/26542
ISSN: 01616420
DOI: 10.1016/j.ophtha.2007.11.015
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

92
checked on Dec 4, 2017

Page view(s)

146
checked on Dec 7, 2017

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.