Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.neulet.2010.03.038
Title: Early event-related potentials changes during simple mental calculation in Chinese older adults with mild cognitive impairment: A case-control study
Authors: Li, X.
Zhang, Y.
Meng, Q.
Feng, L. 
Keywords: Arithmetic calculation
Event-related potentials (ERP)
Mild cognitive impairment
Issue Date: 2010
Source: Li, X., Zhang, Y., Meng, Q., Feng, L. (2010). Early event-related potentials changes during simple mental calculation in Chinese older adults with mild cognitive impairment: A case-control study. Neuroscience Letters 475 (1) : 29-32. ScholarBank@NUS Repository. https://doi.org/10.1016/j.neulet.2010.03.038
Abstract: The aim was to examine early event-related potential (ERP) changes during mental arithmetic calculation task in mild cognitive impairment patients compared to healthy elderly. 16 mild cognitive impairment (MCI) subjects and 16 healthy Chinese older adults were studied. Event-related potentials were elicited using a simple mental calculation task. Performance on arithmetic calculation task, and the latency and amplitude of early event-related potential components (N1, P1, N170, and P2) were compared between the two groups. The reaction time of MCI group was significantly longer than that of control group (1691.03 ± 94.59 vs 1539.55 ± 27.76, P<0.01). The correct rate of MCI group (0.9463 ± 0.04) was significantly lower than that of control group (0.9776 ± 0.02, P< 0.01). The latency of temporal-occipital N170 and central-prefrontal P2 of MCI group were significantly prolonged compared to controls. MCI subjects presented significantly higher P2 amplitude. Compared with healthy controls, N170 was significantly lower at left temporal-occipital region and higher at right temporal-occipital region in mild cognitive impairment. Mild cognitive impairment patients had deficit on simple calculation. The early arithmetic calculation processing mechanism of mild cognitive impairment patients may be different from normal people. © 2010 Elsevier Ireland Ltd.
Source Title: Neuroscience Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/24100
ISSN: 03043940
DOI: 10.1016/j.neulet.2010.03.038
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

5
checked on Jan 17, 2018

WEB OF SCIENCETM
Citations

5
checked on Jan 8, 2018

Page view(s)

201
checked on Jan 15, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.