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https://doi.org/10.3201/eid2408.171883
| Title: | Distinguishing zika and dengue viruses through simple clinical assessment, Singapore | Authors: | Yan, G Pang, L Cook, A.R Ho, H.J Win, M.S Khoo, A.L Wong, J.G.X Lee, C.K Yan, B Jureen, R Ho, S.S Lye, D.C Tambyah, P.A Leo, Y.S Fisher, D Oon, J Bagdasarian, N Chow, A Smitasin, N Chai, L.Y.A |
Keywords: | alanine aminotransferase aspartate aminotransferase nonstructural protein 1 virus RNA adult aged arthralgia Article biochemical analysis blood analysis case control study clinical assessment cohort analysis conjunctivitis dengue Dengue virus diagnostic accuracy female fever headache human major clinical study male monocyte count monocytosis myalgia nonhuman platelet count predictive value receiver operating characteristic reverse transcription polymerase chain reaction sensitivity and specificity Singapore symptomatology urinalysis validation process Youden index Zika fever Zika virus Aedes animal dengue Dengue virus differential diagnosis fever leukocyte count middle aged mosquito vector myalgia pathophysiology transmission viral conjunctivitis virology Zika fever Zika virus Adult Aedes Aged Animals Case-Control Studies Cohort Studies Conjunctivitis, Viral Dengue Dengue Virus Diagnosis, Differential Female Fever Humans Leukocyte Count Male Middle Aged Mosquito Vectors Myalgia Platelet Count ROC Curve Singapore Zika Virus Zika Virus Infection |
Issue Date: | 2018 | Publisher: | Centers for Disease Control and Prevention (CDC) | Citation: | Yan, G, Pang, L, Cook, A.R, Ho, H.J, Win, M.S, Khoo, A.L, Wong, J.G.X, Lee, C.K, Yan, B, Jureen, R, Ho, S.S, Lye, D.C, Tambyah, P.A, Leo, Y.S, Fisher, D, Oon, J, Bagdasarian, N, Chow, A, Smitasin, N, Chai, L.Y.A (2018). Distinguishing zika and dengue viruses through simple clinical assessment, Singapore. Emerging Infectious Diseases 24 (8) : 1565-1568. ScholarBank@NUS Repository. https://doi.org/10.3201/eid2408.171883 | Abstract: | Dengue virus and Zika virus coexist in tropical regions in Asia where healthcare resources are limited; differentiating the 2 viruses is challenging. We showed in a case–control discovery cohort, and replicated in a validation cohort, that the diagnostic indices of conjunctivitis, platelet count, and monocyte count reliably distinguished between these viruses. © 2018, Centers for Disease Control and Prevention (CDC). All rights reserved. | Source Title: | Emerging Infectious Diseases | URI: | https://scholarbank.nus.edu.sg/handle/10635/175107 | ISSN: | 1080-6040 | DOI: | 10.3201/eid2408.171883 |
| Appears in Collections: | Staff Publications Elements |
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