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https://scholarbank.nus.edu.sg/handle/10635/145436
| Title: | CYTOTOXICITY MEDIATED BY L-AMINO ACID OXIDASE ISOLATED FROM THE VENOM OF CROTALUS MITCHELLII PYRRHUS | Authors: | TAN KOK KEONG | Keywords: | snake venom LAAO, cytotoxicity, cancer cells, oxidative stress, apoptosis | Issue Date: | 22-Jan-2018 | Citation: | TAN KOK KEONG (2018-01-22). CYTOTOXICITY MEDIATED BY L-AMINO ACID OXIDASE ISOLATED FROM THE VENOM OF CROTALUS MITCHELLII PYRRHUS. ScholarBank@NUS Repository. | Abstract: | This thesis examines the mechanism of cytotoxicity of an L-amino acid oxidase isolated from snake venom in prostate cancer cell line. The enzyme causes oxidative stress, induces ER stress and activates autophagy in the cells in vitro, leading to the activation of apoptosis. | URI: | http://scholarbank.nus.edu.sg/handle/10635/145436 |
| Appears in Collections: | Ph.D Theses (Open) |
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| File | Description | Size | Format | Access Settings | Version | |
|---|---|---|---|---|---|---|
| Live cell_Control.mp4 | 33.89 MB | MP4 | OPEN | None | Preview online | |
| Live cell_Treated.mp4 | 30.88 MB | MP4 | OPEN | None | Preview online | |
| TanKK_Final thesis_signed.pdf | 4.97 MB | Adobe PDF | OPEN | None | View/Download |
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