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https://scholarbank.nus.edu.sg/handle/10635/134571
| Title: | EXPLORING THE ALLOSTERIC INHIBITION MECHANISM OF HUMAN KIDNEY TYPE GLUTAMINASE TO ARREST CANCER CELL PROLIFERATION AND INVESTIGATING HAKAI MEDIATED UBIQUITINATION TOWARDS CONTROLLING CANCER CELL MIGRATION | Authors: | SARATH RAMACHANDRAN | Keywords: | KGA, hakai, compound 968, CB839, CBTBP | Issue Date: | 22-Jan-2016 | Citation: | SARATH RAMACHANDRAN (2016-01-22). EXPLORING THE ALLOSTERIC INHIBITION MECHANISM OF HUMAN KIDNEY TYPE GLUTAMINASE TO ARREST CANCER CELL PROLIFERATION AND INVESTIGATING HAKAI MEDIATED UBIQUITINATION TOWARDS CONTROLLING CANCER CELL MIGRATION. ScholarBank@NUS Repository. | Abstract: | The development and progression of cancer can be associated with certain hallmarks. Two among them are the altered cell metabolism (Warburg effect), and cancer cell invasion/progression mediated by post-translational modulation of cell signaling. In this thesis we have attempted to explore these two hallmarks towards understanding different avenues to arrest cancer cell growth | URI: | http://scholarbank.nus.edu.sg/handle/10635/134571 |
| Appears in Collections: | Ph.D Theses (Open) |
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| File | Description | Size | Format | Access Settings | Version | |
|---|---|---|---|---|---|---|
| RamachandranS.pdf | 37.09 MB | Adobe PDF | OPEN | None | View/Download |
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