Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/133363
Title: Gastric adenocarcinoma occurring in a young patient with common variable immunodeficiency syndrome
Authors: Yap, Y.L.
So, J.B.Y. 
Keywords: B-cell deficiency
Common variable immunodeficiency syndrome
Gastric adenocarcinoma
Hypogammaglobinaemia
Issue Date: Jun-2009
Source: Yap, Y.L., So, J.B.Y. (2009-06). Gastric adenocarcinoma occurring in a young patient with common variable immunodeficiency syndrome. Singapore Medical Journal 50 (6) : e201-e203. ScholarBank@NUS Repository.
Abstract: Patients with common variable immunodeficiency syndrome (CVID) have an increased risk of gastric adenocarcinoma. We describe a case of gastric adenocarcinoma in a 29-year-old man with CVID. He complained of dyspepsia and weight loss. Endoscopy showed an antral lesion. He underwent subtotal gastrectomy with postoperative adjuvant chemoradiation, and remained disease-free for three years. CVID is a predisposing factor for gastric adenocarcinoma. Gastric complaints are common among these patients and should be viewed seriously. Endoscopy is performed to detect any pathology. Premalignant conditions like chronic atrophic gastritis, intestinal metaplasia and dysplasia require regular endoscopic surveillance in these high-risk patients.
Source Title: Singapore Medical Journal
URI: http://scholarbank.nus.edu.sg/handle/10635/133363
ISSN: 00375675
Appears in Collections:Staff Publications

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