HLA and nasopharyngeal carcinoma in Malays

Please use this identifier to cite or link to this item: https://doi.org/10.1038/bjc.1985.52

Title:	HLA and nasopharyngeal carcinoma in Malays
Authors:	Chan, S.H. Chew, C.T. Prasad, U. Wee, G.B. Srinivasan, N. Kunaratnam, N.
Issue Date:	1985
Citation:	Chan, S.H., Chew, C.T., Prasad, U., Wee, G.B., Srinivasan, N., Kunaratnam, N. (1985). HLA and nasopharyngeal carcinoma in Malays. British Journal of Cancer 51 (3) : 389-392. ScholarBank@NUS Repository. https://doi.org/10.1038/bjc.1985.52
Abstract:	HLA associations were observed in unrelated Malay patients with nasopharyngeal carcinoma (NPC). HLA-B18 was observed in 18/45 (40%) Malay NPC patients compared to 22/167 (13%) Malay normals (P = 0.0027, RR = 4.4). The frequency of HLA-B17, one of the antigens associated with Chinese NPC, was also increased among Malay NPC (13/45 29%) compared to controls (18/167 11%; P = 0.003, Pc = 0.07 RR = 3.4). Similar to the findings among Chinese NPC, the frequency of B17 was higher in early onset (≤30 years) Malay NPC resulting in a higher relative risk (RR = 5.0).
Source Title:	British Journal of Cancer
URI:	http://scholarbank.nus.edu.sg/handle/10635/133326
ISSN:	00070920
DOI:	10.1038/bjc.1985.52
Appears in Collections:	Staff Publications

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