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|Title:||HLA and allopurinol drug eruption|
|Authors:||Chan, S.H. |
|Source:||Chan, S.H., Tan, T. (1989). HLA and allopurinol drug eruption. Dermatologica 179 (1) : 32-33. ScholarBank@NUS Repository.|
|Abstract:||Strong HLA associations were found in Southern Chinese patients with skin eruptions due to allopurinol. The positive associations were with AW33 (Pc = 1.7 x 10-5; relative risk [RR] = 15.0, 95% confidence limit 5.2-42.9) with B17/BW58 (Pc = 2.9 x 10-9; RR = 46.3, 95% confidence limit 10.3-209.2). The negative association was with A2 (Pc = 8.3 x 10-5, RR = 0). The findings suggested a genetic predisposition to cutaneous drug reactions.|
|Appears in Collections:||Staff Publications|
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