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https://scholarbank.nus.edu.sg/handle/10635/132556
| Title: | HLA and allopurinol drug eruption | Authors: | Chan, S.H. Tan, T. |
Issue Date: | 1989 | Citation: | Chan, S.H., Tan, T. (1989). HLA and allopurinol drug eruption. Dermatologica 179 (1) : 32-33. ScholarBank@NUS Repository. | Abstract: | Strong HLA associations were found in Southern Chinese patients with skin eruptions due to allopurinol. The positive associations were with AW33 (Pc = 1.7 x 10-5; relative risk [RR] = 15.0, 95% confidence limit 5.2-42.9) with B17/BW58 (Pc = 2.9 x 10-9; RR = 46.3, 95% confidence limit 10.3-209.2). The negative association was with A2 (Pc = 8.3 x 10-5, RR = 0). The findings suggested a genetic predisposition to cutaneous drug reactions. | Source Title: | Dermatologica | URI: | http://scholarbank.nus.edu.sg/handle/10635/132556 | ISSN: | 00119075 |
| Appears in Collections: | Staff Publications |
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