Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/131978
Title: Serum tumor markers in patients on dialysis and kidney transplantation.
Authors: Lye, W.C.
Tambyah, P.
Leong, S.O.
Lee, E.J. 
Issue Date: 1994
Source: Lye, W.C., Tambyah, P., Leong, S.O., Lee, E.J. (1994). Serum tumor markers in patients on dialysis and kidney transplantation.. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 10 : 109-111. ScholarBank@NUS Repository.
Abstract: Tumor markers play an important role in the assessment of patients with some types of malignant tumors. We studied the effects of dialysis and transplantation on the serum levels of five tumor markers; alpha-fetoprotein (AFP), carcino-embryonic antigen (CEA), cancer antigen-125 (CA-125), cancer antigen-19.9 (CA-19.9), and prostate specific antigen (PSA). Serum tumor markers were measured in patients who-had been on dialysis treatment or had a renal transplant for at least one month. Four groups of 30 patients each (hemodialysis, peritoneal dialysis, renal transplant, and normal controls) were studied. Age and sex distribution were comparable between the dialysis and control groups, but the age was significantly younger in the transplant group. Serum AFP and PSA levels were within normal limits in the dialysis and transplant patients. Serum tumor markers, which were raised in the hemodialysis and peritoneal dialysis patients compared to transplant patients and controls, include: CEA (4.5 +/- 2.7 and 5.1 +/- 3.0 vs 1.7 +/- 1.2 and 2.7 +/- 1.2, p < 0.001); CA-125 (41.1 +/- 43.8 and 18.9 +/- 12.7 vs 13.4 +/- 5.7 and 6.1 +/- 4.9, p < 0.001 and p < 0.05); and CA-19.9 (66.0 +/- 60.4 and 66.2 +/- 76.5 vs 20.2 +/- 12.3 and 5.3 +/- 4.5, p < 0.001). Raised CEA, CA-125, and CA-19.9 levels were detected in 37%, 10%, and 53% of peritoneal dialysis patients and 17%, 27%, and 57% of hemodialysis patients. Although the mean serum CEA, CA-125, and CA-19.9 levels were higher in the transplant patients compared to controls.(ABSTRACT TRUNCATED AT 250 WORDS)
Source Title: Advances in peritoneal dialysis. Conference on Peritoneal Dialysis
URI: http://scholarbank.nus.edu.sg/handle/10635/131978
ISSN: 11978554
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

30
checked on Jan 14, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.