Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/131757
Title: Immunotoxins: The potential in cancer treatment
Authors: Ren, E.C. 
Issue Date: 1990
Citation: Ren, E.C. (1990). Immunotoxins: The potential in cancer treatment. Annals of the Academy of Medicine Singapore 19 (2) : 240-243. ScholarBank@NUS Repository.
Abstract: Since its development in 1975, monoclonal antibody (mAb) technology has greatly enhanced our ability to analyse complex antigenic systems as well as improve the sensitivity and speed of many diagnostic tests. In particular, the study of tumour associated antigens using mAbs have revealed that many transformed cell phenotypes have useful markers on their plasma membrane, cytoplasm, or as secreted forms which can be used in developing diagnostic assays. Therapeutic application of these anti-tumour mAbs has however, been slow relative to the research and diagnostic applications. This article will discuss how the therapeutic effectiveness of anti-tumour mAbs can be enhanced by coupling them to drugs, toxins or radionucleids; and review the current advances and problems related to the application of these mAb conjugates.
Source Title: Annals of the Academy of Medicine Singapore
URI: http://scholarbank.nus.edu.sg/handle/10635/131757
ISSN: 03044602
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

8
checked on Oct 18, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.