Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/131232
Title: Hereditary protein C deficiency--the first symptomatic family in Singapore.
Authors: Kueh, Y.K. 
Radhakrishnan, U.
Han, P. 
Issue Date: Jul-1989
Source: Kueh, Y.K., Radhakrishnan, U., Han, P. (1989-07). Hereditary protein C deficiency--the first symptomatic family in Singapore.. Annals of the Academy of Medicine Singapore 18 (4) : 456-458. ScholarBank@NUS Repository.
Abstract: Protein C is an important physiological inhibitor of coagulation. A deficiency of this protein is a recognised cause of recurrent venous thromboembolism. The assay for protein C was not locally available until recently. Our investigation of a young Malay woman who had sustained two previous pulmonary emboli led us to identify the first family in Singapore with this familial disorder. The definitive diagnosis of symptomatic protein C deficiency justifies longterm anticoagulant therapy in two members of this family. We now systematically screen all young adults who present with the first episode of deep venous thrombosis or pulmonary embolism irrespective of whether the event is spontaneous or seemingly precipitated.
Source Title: Annals of the Academy of Medicine Singapore
URI: http://scholarbank.nus.edu.sg/handle/10635/131232
ISSN: 03044602
Appears in Collections:Staff Publications

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