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https://scholarbank.nus.edu.sg/handle/10635/130099
| Title: | Run probability of high-order seed patterns and its applications to finding good transition seeds | Authors: | Yang, J.L. Zhang, L.X. |
Keywords: | High-order seed pattern Run statistics Sensitivity analysis Transition seed |
Issue Date: | 2008 | Citation: | Yang, J.L., Zhang, L.X. (2008). Run probability of high-order seed patterns and its applications to finding good transition seeds. Series on Advances in Bioinformatics and Computational Biology 6 : 123-132. ScholarBank@NUS Repository. | Abstract: | Transition seeds exhibit a good tradeoff between sensitivity and specificity for homology search in both coding and non-coding regions. But, identifying good transition seeds is extremely hard. We study the hit probability of high-order seed patterns. Based on our theoretical results, we propose an efficient method for ranking transition seeds for seed design. | Source Title: | Series on Advances in Bioinformatics and Computational Biology | URI: | http://scholarbank.nus.edu.sg/handle/10635/130099 | ISBN: | 9781848161085 | ISSN: | 17516404 |
| Appears in Collections: | Staff Publications |
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