Sustainable tripartite weight management: Towards euglycaemia and normalized metabolic function in the Metabolic Syndrome (Part 1)

Abstract

Over 2 billion people face premature death and serious illnesses such as diabetes, heart disease, stroke, hypertension and certain types of cancer, through excess body weight. Despite decades of public campaign on healthy diet and exercise, and the efficacy of anti-obesity drugs and bariatric surgery; the obesity pandemic has not abated. A key reason being, in clinical reality, weight therapy must enable patients to achieve energy restriction and normalized metabolism, while "eating more and exercising less". This seemingly paradoxical approach is now possible because of advanced food derivatives, coupled to cognate formulations, pharmacological research and systematic bariatric lifestyle intervention.