Immediate changes in intraocular pressure after laser peripheral iridotomy in primary angle-closure suspects

Abstract

Purpose: To determine the immediate changes in intraocular pressure (IOP) after laser peripheral iridotomy in primary angle-closure suspects. Design: Prospective, randomized controlled trial (split-body design). Participants: Seven hundred thirty-four Chinese people 50 to 70 years of age. Methods: Primary angle-closure suspects underwent iridotomy using a neodymium: yttriumaluminumgarnet laser in 1 randomly selected eye, with the fellow eye serving as a control. Intraocular pressure was measured using Goldmann applanation tonometry before treatment and 1 hour and 2 weeks after treatment. Total energy used and complications were recorded. Risk factors for IOP rise after laser peripheral iridotomy were investigated. Main Outcome Measures: Intraocular pressure. Results: The proportion of treated eyes with an IOP spike (an elevation of