Please use this identifier to cite or link to this item:
|Title:||Epithelial-Mesenchymal Transitions in Development and Disease|
|Authors:||Thiery, J.P. |
|Source:||Thiery, J.P., Acloque, H., Huang, R.Y.J., Nieto, M.A. (2009-11-25). Epithelial-Mesenchymal Transitions in Development and Disease. Cell 139 (5) : 871-890. ScholarBank@NUS Repository. https://doi.org/10.1016/j.cell.2009.11.007|
|Abstract:||The epithelial to mesenchymal transition (EMT) plays crucial roles in the formation of the body plan and in the differentiation of multiple tissues and organs. EMT also contributes to tissue repair, but it can adversely cause organ fibrosis and promote carcinoma progression through a variety of mechanisms. EMT endows cells with migratory and invasive properties, induces stem cell properties, prevents apoptosis and senescence, and contributes to immunosuppression. Thus, the mesenchymal state is associated with the capacity of cells to migrate to distant organs and maintain stemness, allowing their subsequent differentiation into multiple cell types during development and the initiation of metastasis. © 2009 Elsevier Inc. All rights reserved.|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Mar 8, 2018
WEB OF SCIENCETM
checked on Feb 6, 2018
checked on Mar 11, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.