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|Title:||Solid-phase functionalization of heterocycles by direct lithiation|
|Source:||Li, Z.,Ganesan, A. (1998-04). Solid-phase functionalization of heterocycles by direct lithiation. Synlett (4) : 405-406. ScholarBank@NUS Repository.|
|Abstract:||Lithiation of polymer-bound 3-furanmethanol and 3-thiophenemethanol followed by the addition of electrophiles and resin cleavage afforded 2,4-disubsituted furans and thiophenes respectively in good yield. The 2,4-substituted thiophene can also be further lithiated on solid-phase at C-5 to give 2,3,5-substituted thiophenes.|
|Appears in Collections:||Staff Publications|
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