Renal dysfunction in workers exposed to inorganic lead

Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/113737

Title:	Renal dysfunction in workers exposed to inorganic lead
Authors:	Lim, Y.C. Chia, K.S. Ong, H.Y. Ng, V. Chew, Y.L.
Keywords:	α-1 microglobulin β-2 microglobulin Creatinine clearnance N-acetyl-β-D-glucosaminidase
Issue Date:	2001
Citation:	Lim, Y.C.,Chia, K.S.,Ong, H.Y.,Ng, V.,Chew, Y.L. (2001). Renal dysfunction in workers exposed to inorganic lead. Annals of the Academy of Medicine Singapore 30 (2) : 112-117. ScholarBank@NUS Repository.
Abstract:	Introduction: We studied the relationship between renal dysfunction and occupational lead exposure in a local factory. Materials and Methods: A cross-sectional study with a cohort component was conducted with 55 male workers of a factory producing PVC stabilisers at subjects. Workers from this factory have been followed up with 6-monthly blood lead measurements since 1982. Two indices of overall lead exposure, i.e. the number of times a worker's blood lead exceeded 40 μg/dL (Pb B40) and cumulative blood lead index (PbBint), were obtained from this data. Recent blood lead concentration (PbB) was measured. 4-hour creatinine clearance and various other urinary and serum markers of renal dysfunction were used as effect indices. Results: There was no relationship between PbB and any of the renal markers. However, creatinine clearance decreased significantly (P
Source Title:	Annals of the Academy of Medicine Singapore
URI:	http://scholarbank.nus.edu.sg/handle/10635/113737
ISSN:	03044602
Appears in Collections:	Staff Publications

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