Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/112290
Title: Reperfusion strategy and mortality in ST-elevation myocardial infarction among patients with and without impaired renal function
Authors: Chan, M.Y.
Becker, R.C.
Sim, L.-L.
Tan, V.
Lee, C.-H.
Low, A.F.H.
Teo, S.-G. 
Ng, K.-S.
Tan, H.-C.
Yeo, T.-C.
Keywords: Acute coronary syndrome
Fibrinolysis
Kidney disease
Primary angioplasty
Issue Date: Mar-2010
Source: Chan, M.Y.,Becker, R.C.,Sim, L.-L.,Tan, V.,Lee, C.-H.,Low, A.F.H.,Teo, S.-G.,Ng, K.-S.,Tan, H.-C.,Yeo, T.-C. (2010-03). Reperfusion strategy and mortality in ST-elevation myocardial infarction among patients with and without impaired renal function. Annals of the Academy of Medicine Singapore 39 (3) : 179-184. ScholarBank@NUS Repository.
Abstract: Introduction: Several randomised controlled trials have demonstrated better outcomes with primary percutaneous coronary intervention (PCI) over fibrinolytic therapy in the treatment of patients with ST-segment elevation myocardial infarction (STEMI) and normal renal function. Whether this benefit extends to patients with impaired renal function is uncertain. Materials and Methods: We studied 1672 patients with STEMI within 12 hours of symptom onset who were admitted to 2 major public hospitals in Singapore from 2000 to 2002. All patients received either upfront fibrinolytic or PCI as determined by the attending cardiologist. Serum creatinine was measured on admission and the glomerular filtration rate (GFR) was determined using the Modification of Diet in Renal Disease equation. The impact of reperfusion strategy on 30-ay mortality was then determined for patients with GFR ≥60 mL min-1 1.73 m-2 and GFR
Source Title: Annals of the Academy of Medicine Singapore
URI: http://scholarbank.nus.edu.sg/handle/10635/112290
ISSN: 03044602
Appears in Collections:Staff Publications

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