Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ijcard.2007.07.074
Title: A novel drug-eluting stent using bioabsorbable polymer technology: Two-year follow-up of the CURAMI registry
Authors: Tin Hay, E.
Hou, X.-M.
Lim, J.
Low, A.
Teo, S.-G. 
Tan, H.-C.
Lee, C.-H.
Keywords: Bioabsorbable
Coronary
Drug-eluting stent
Polymer
Stent thrombosis
Issue Date: 9-Jan-2009
Source: Tin Hay, E., Hou, X.-M., Lim, J., Low, A., Teo, S.-G., Tan, H.-C., Lee, C.-H. (2009-01-09). A novel drug-eluting stent using bioabsorbable polymer technology: Two-year follow-up of the CURAMI registry. International Journal of Cardiology 131 (2) : 272-274. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ijcard.2007.07.074
Abstract: Background: There are safety concerns on drug-eluting stents (DESs) using durable polymer. The long-term outcome of next generation DESs using bioabsorbable polymer technology remains unknown. Methods: From March to June, 2005, a novel sirolimus-eluting (170 μg/cm2), bioabsorbable polymer (PLA and PLGA, eroded over 45 days) coated stent was implanted for treatment of acute myocardial infarction (AMI) in 49 patients (male 86%, age 55 + 10 years, diabetes 31%). All culprits were de novo lesions in the native coronary artery. On discharge, aspirin and clopidogrel for 3 months followed by life-long aspirin were prescribed. Angiographic follow-up was performed at 8 months. Clinical follow-up was performed at 4, 9 and 24 months. Results: Angiographic success rate was 100%. In-hospital adverse events consisted of 1 death (2%). All except one patient (due to aspirin allergy) were compliant to the 3 months dual antiplatelet therapy, and there was no adverse event during this period. One patient developed re-infarction in another coronary territory at 6 months. Twenty-seven patients (56%) underwent 8-month angiographic follow-up (Table 3). At 24 months, 6 patients had 7 major adverse cardiac events (12.2%, 1 death, 2 re-infarctions and 4 target lesion revascularizations). There were no incidences of subacute or late stent thrombosis. Conclusions: The Cura stent, using bioabsorbable polymer technology, appears to be safe at 2 years follow-up. Although the angiographic follow-up parameters were unfavorable, this report paves the way for further studies on DES using bioabsorbable polymer technology. © 2007 Elsevier Ireland Ltd. All rights reserved.
Source Title: International Journal of Cardiology
URI: http://scholarbank.nus.edu.sg/handle/10635/112211
ISSN: 01675273
DOI: 10.1016/j.ijcard.2007.07.074
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

6
checked on Apr 3, 2018

WEB OF SCIENCETM
Citations

4
checked on Apr 3, 2018

Page view(s)

42
checked on Apr 20, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.