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https://doi.org/10.1016/0168-9525(96)10018-4
Title: | Small is beautiful: Comparative genomics with the pufferfish (Fugu rubripes) | Authors: | Elgar, G. Sandford, R. Aparicio, S. Macrae, A. Venkatesh, B. Brenner, S. |
Issue Date: | Apr-1996 | Citation: | Elgar, G., Sandford, R., Aparicio, S., Macrae, A., Venkatesh, B., Brenner, S. (1996-04). Small is beautiful: Comparative genomics with the pufferfish (Fugu rubripes). Trends in Genetics 12 (4) : 145-150. ScholarBank@NUS Repository. https://doi.org/10.1016/0168-9525(96)10018-4 | Abstract: | As the Human Genome Project advances, it is clear that the emphasis will switch from accumulation of data to their interpretation. Comparative genomics provides a powerful way in which to analyse sequence data. Indeed, there is already a long list of 'model' organisms, which allow comparative analyses in a variety of ways. The very small vertebrate genome of the pufferfish provides a simple and economical way of comparing sequence data from mammals and fish, representing a large evolutionary divergence and so permitting the identification of essential elements that are still present in both species. These elements include genes and the associated machinery that controls their expression; elements that, in many cases, have survived the test of time. | Source Title: | Trends in Genetics | URI: | http://scholarbank.nus.edu.sg/handle/10635/112196 | ISSN: | 01689525 | DOI: | 10.1016/0168-9525(96)10018-4 |
Appears in Collections: | Staff Publications |
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