Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0040-4039(99)01049-7
Title: A solid-phase equivalent of van Leusen's TosMIC, and its application in oxazole synthesis
Authors: Kulkarni, B.A. 
Ganesan, A. 
Keywords: Combinatorial chemistry
Isocyanides
Oxazoles
Solid-phase synthesis
Issue Date: Jul-1999
Citation: Kulkarni, B.A., Ganesan, A. (1999-07). A solid-phase equivalent of van Leusen's TosMIC, and its application in oxazole synthesis. Tetrahedron Letters 40 (30) : 5633-5636. ScholarBank@NUS Repository. https://doi.org/10.1016/S0040-4039(99)01049-7
Abstract: Polystyrene-SH resin, prepared from Merrifield resin in two steps, was converted to polystyrene-SO2-CH2-NC in three steps. This resin functions as a solid-phase equivalent of p-tolylsulfonylmethyl isocyanide (TosMIC). Thus, reaction with aromatic aldehydes and tetrabutylammonium hydroxide as base yields 5-aryloxazoles.
Source Title: Tetrahedron Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/111768
ISSN: 00404039
DOI: 10.1016/S0040-4039(99)01049-7
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