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https://doi.org/10.1016/S0040-4039(99)01049-7
| Title: | A solid-phase equivalent of van Leusen's TosMIC, and its application in oxazole synthesis | Authors: | Kulkarni, B.A. Ganesan, A. |
Keywords: | Combinatorial chemistry Isocyanides Oxazoles Solid-phase synthesis |
Issue Date: | Jul-1999 | Citation: | Kulkarni, B.A., Ganesan, A. (1999-07). A solid-phase equivalent of van Leusen's TosMIC, and its application in oxazole synthesis. Tetrahedron Letters 40 (30) : 5633-5636. ScholarBank@NUS Repository. https://doi.org/10.1016/S0040-4039(99)01049-7 | Abstract: | Polystyrene-SH resin, prepared from Merrifield resin in two steps, was converted to polystyrene-SO2-CH2-NC in three steps. This resin functions as a solid-phase equivalent of p-tolylsulfonylmethyl isocyanide (TosMIC). Thus, reaction with aromatic aldehydes and tetrabutylammonium hydroxide as base yields 5-aryloxazoles. | Source Title: | Tetrahedron Letters | URI: | http://scholarbank.nus.edu.sg/handle/10635/111768 | ISSN: | 00404039 | DOI: | 10.1016/S0040-4039(99)01049-7 |
| Appears in Collections: | Staff Publications |
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