Please use this identifier to cite or link to this item:
|Title:||Effects of heart disease on depression treatment: Results from the COMED study|
|Citation:||Kerber, K.B., Wisniewski, S.R., Luther, J.F., Leuchter, A.F., D'Empaire, I., Trivedi, M.H., Rush, A.J. (2012-01). Effects of heart disease on depression treatment: Results from the COMED study. General Hospital Psychiatry 34 (1) : 24-34. ScholarBank@NUS Repository. https://doi.org/10.1016/j.genhosppsych.2011.08.018|
|Abstract:||Objective: To determine the impact of self-reported heart disease (HD) on major depressive disorder (MDD) treatment outcomes. Method: This single-blind, 7-month prospective randomized trial enrolled 665 participants, 18-75 years old, from six primary and nine psychiatric care sites across the USA. Participants had at least moderately severe (baseline 17-item Hamilton Rating Scale of Depression ≥16), nonpsychotic chronic and/or recurrent MDD. Participants with and without self-reported HD were randomized into three treatment groups (1:1:1 ratio): escitalopram plus placebo, bupropion sustained-release plus escitalopram or venlafaxine extended-release plus mirtazapine. The primary outcome (remission) was defined by the last two consecutive 16-item Quick Inventory of Depressive Symptomatology-Self-Report (QIDS-SR 16) ratings: one had to be|
|Source Title:||General Hospital Psychiatry|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jun 19, 2018
WEB OF SCIENCETM
checked on Jun 12, 2018
checked on Mar 12, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.