Please use this identifier to cite or link to this item: https://doi.org/10.1186/1471-2342-12-19
Title: Correlation of anterior segment optical coherence tomography measurements with graft trephine diameter following descemet stripping automated endothelial keratoplasty
Authors: Tan, G.S.
He, M.
Tan, D.T.
Mehta, J.S. 
Issue Date: 23-Jul-2012
Citation: Tan, G.S., He, M., Tan, D.T., Mehta, J.S. (2012-07-23). Correlation of anterior segment optical coherence tomography measurements with graft trephine diameter following descemet stripping automated endothelial keratoplasty. BMC Medical Imaging 12 : -. ScholarBank@NUS Repository. https://doi.org/10.1186/1471-2342-12-19
Abstract: Background: To assess repeatability of the Zhongshan Assessment Program (ZAP) software measurement of Anterior Segment Optical Coherence Tomography (ASOCT) images and correlate with graft trephine diameter following Descemet Stripping Automated Endothelial Keratoplasty (DSAEK). Methods: Retrospectively evaluated interventional case series. 121 consecutive eyes undergoing DSAEK over a 26 month period underwent ASOCT imaging 1month after their surgery. ASOCT images were processed using ZAP software which measured the graft and cornea parameters including anterior and posterior graft arc length and cord length, posterior cornea arc length (PCAL) and anterior chamber width.Results: The graft measurements showed good repeatability on ASOCT using ZAP with high intra class coefficient and small variation in the coefficient of variation. On ASOCT, the mean recipient PCAL was 12.99+/-0.69mm and the anterior chamber width was 11.16+/-0.57mm. The mean Graft anterior arc length was 9.69+/-0.66mm and the mean Graft anterior cord length was 8.92+/-2.94mm. The mean graft posterior arc length was 9.24+/-0.75mm and the mean graft posterior cord length was 8.15+/-0.57mm. Graft posterior arc length (rho=0.788, p< 0.001) correlated best with intra-operative graft trephine diameter. The mean ratio of posterior graft arc length to PCAL was 0.712 +/- 0.056.Conclusions: We have validated the repeatability of the ZAP software for DSAEK graft measurements from ASOCT images and shown that the graft arc length parameters calculated from the ASOCT images correlate well with the intra-operative graft trephine diameter. This software may help surgeons determine the optimal DSAEK graft size based on pre-operative ASOCT measurements of the recipient eye. © 2012 Tan et al.; licensee BioMed Central Ltd.
Source Title: BMC Medical Imaging
URI: http://scholarbank.nus.edu.sg/handle/10635/110513
ISSN: 14712342
DOI: 10.1186/1471-2342-12-19
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

4
checked on Oct 20, 2018

WEB OF SCIENCETM
Citations

4
checked on Oct 3, 2018

Page view(s)

30
checked on Sep 28, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.