Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.tem.2006.07.006
Title: Retinal vascular manifestations of metabolic disorders
Authors: Nguyen, T.T.
Wong, T.Y. 
Issue Date: Sep-2006
Citation: Nguyen, T.T., Wong, T.Y. (2006-09). Retinal vascular manifestations of metabolic disorders. Trends in Endocrinology and Metabolism 17 (7) : 262-268. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tem.2006.07.006
Abstract: Metabolic diseases have profound effects on the structure and function of the retinal circulation. The recent development of retinal photography and digital imaging has enabled more precise documentation of diabetic retinopathy, as well as other retinal microvascular changes, such as retinal arteriolar narrowing, venular dilation and isolated retinopathy signs in nondiabetic individuals. These retinal microvascular signs have been shown to be associated with long-term risks of type 2 diabetes and hypertension, components of the metabolic syndrome (e.g. obesity, dyslipidemia), and a range of macro- and micro-vascular conditions (e.g. stroke, cardiovascular mortality). There is evidence that endothelial dysfunction and inflammation might be possible mechanisms involved in the development of various retinal microvascular changes in patients with diabetes, hypertension and other metabolic disorders. Further understanding of how these processes influence the retinal vasculature might help to elucidate the diverse vascular manifestations of metabolic diseases. © 2006 Elsevier Ltd. All rights reserved.
Source Title: Trends in Endocrinology and Metabolism
URI: http://scholarbank.nus.edu.sg/handle/10635/109861
ISSN: 10432760
DOI: 10.1016/j.tem.2006.07.006
Appears in Collections:Staff Publications

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